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FRONTLINE Plus for Dogs Flea & Tick Large Breed Dog Spot Treatment, 45 - 88 lbs
Break the flea life cycle with FRONTLINE® Plus. Specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations.
FRONTLINE Plus for Dogs Flea & Tick Large Breed Dog Spot Treatment, 45 - 88 lbs
Item #: 49833403

FRONTLINE Plus for Dogs Flea & Tick Large Breed Dog Spot Treatment, 45 - 88 lbs

Item #: 49833403
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Break the flea life cycle with FRONTLINE® Plus. Specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations.
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What Stands Out

Broad Spectrum Protection
Effectively targets fleas, ticks, and chewing lice, ensuring comprehensive protection for your dog against multiple pests, setting it apart from single-action treatments.
Long-Lasting Formula
Provides up to 30 days of protection with a single application, reducing the frequency of treatments and ensuring peace of mind for dog owners.
Large Breed Focused
Specially formulated for dogs weighing between 45-88 lbs, delivering high-performance protection tailored specifically for larger breeds.

Product Details

Protect your dog from fleas and ticks with FRONTLINE® Plus, a fast-acting and waterproof topical treatment. Kills fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. Suitable for puppies as young as 8 weeks old. Subscribe & save today! Shop at Ubuy Cayman Islands
  • Fast-acting and long-lasting flea and tick treatment
  • Kills fleas, flea eggs, flea larvae, chewing lice, and ticks
  • Specifically formulated to break the flea life cycle
  • Trusted by pet owners for over 20 years
  • Suitable for puppies as young as eight weeks old and weighing 5 pounds or more
  • Easy to apply with one monthly dose for 30 days of protection
BrandFRONTLINE
Animal typeDog
Weight rangeLarge
Pet sizeLarge
Minimum weight1 lb (450 grams)
Max Weight132 lb (59.87 kg)
Parasite typeLice
Protection period30 days
Medicine formTopical
InstructionsREAD ENTIRE LABEL BEFORE EACH USE. To apply, simply follow these instructions and repeat every 30 days: Use scissors to separate one FRONTLINEu00ae Plus for Dogs blister and cut along dotted line to peel down foil to remove the applicator. Open the applicator by holding upright with foil side toward you and snap applicator tip. Next, part your dog's hair between the shoulder blades. Place the applicator tip just above the skin and squeeze. Apply entire contents of the applicator in a single spot directly onto the dog's skin. Do not apply on top of the haircoat. Avoid contact with treated area until dry. Do not allow your dog to ingest this product. [Do not apply to dogs weighing less than [5 lbs.] [23 lbs.] [45 lbs.] [89 lbs.] or younger than 8 weeks of age.][Do not use two applicators for dogs weighing more than 132 lbs.] Do not use more than one application per dog per month.
Pet flea & tick treatment typeFlea & Tick Treatment
Animal lifestageAll Lifestages
Active ingredientsFipronil, (S)-methoprene
FeaturesWaterproof
Ingredient propertiesAntiparasitic
SizeOne Size
Net content statement8 doses
Product net content uomCount
Product net content parent8 Count
Items included8 doses
Count per pack8
Accessories includedFlea and Tick Topical
Treatment effective time30 days
Treatment time30 days
Ingredient preferenceAluminum-Free
Dispenser styleSqueeze
Recommended useAt-Home
Result time30 days
Animal health concernParasite
Stop use indicationsSee Packaging label.
Topical medication formLiquids
DosageOne dose every 30 days

Who Should Buy?

Suitable For
  • Large Dog Owners

    Ideal for owners of large breed dogs weighing between 45 to 88 lbs needing effective flea and tick protection.

  • Outdoor Dogs

    Best suited for dogs that frequently spend time outdoors, exposing them to fleas and ticks in various environments.

  • Long-lasting Protection

    Users seeking a solution that provides up to 30 days of protection against fleas and ticks with just one application.

Not Suitable For
  • Small Breeds

    Not suitable for small breeds or puppies under 45 lbs, which require different flea and tick treatment formulations.

Product Description

FRONTLINE Plus for Dogs Flea & Tick Large Breed Dog Spot Treatment, 45 - 88 lbs

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Customer Questions & Answers

  • Question: How to Shop FRONTLINE Plus for Dogs Flea & Tick Large Breed Online From Ubuy?

    Answer: It’s easy to shop FRONTLINE Plus for Dogs Flea & Tick Large Breed online from Ubuy. You just have to search for the product, choose your shipping method while checking out and get it delivered to your location.
  • Question: Is FRONTLINE Plus for Dogs Flea & Tick Large Breed Available to Shop Online in Cayman Islands?

    Answer: Yes, at Ubuy Cayman Islands this product is available for you to shop at a reasonable price. The FRONTLINE Plus for Dogs Flea & Tick Large Breed is not available locally but you can trust us with our express shipping services.
  • Question: How Long Does It Take to Get Product After Placing the Order?

    Answer: The delivery time of your ordered product varies as per what you've ordered and the shipping method that you've chosen. The estimated delivery time is mentioned during the checkout process, so be carefree while shopping.

FRONTLINE Pets Subscription Editorial Review

The Frontline Plus flea and tick treatment has received numerous positive reviews from customers. Many users have expressed their satisfaction with the product, noting that it effectively eliminates fleas and ticks from their pets. One customer mentioned that after four years of using the product, their pets were finally flea-free. Another user highlighted that their pet was no longer scratching and biting after using Frontline Plus. Customers also appreciated that the product did not make their pets sick and provided peace of mind in preventing flea and tick infestations. One user mentioned that the product worked even in an environment with a high prevalence of ticks and fleas. Overall, customers have found Frontline Plus to be a reliable and efficient solution for protecting their pets from fleas and ticks.

Customer Reviews & Ratings

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Pros

  • Effectively eliminates fleas and ticks
  • Provides peace of mind for pet owners
  • Does not make pets sick
  • Works in environments with high flea and tick prevalence

Cons

  • No notable Cons mentioned in the reviews

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“Excellent quality and original too,when ubuy send original things I will appreciate that ,I very satisfied thank you”

23 July 2026 · via Trustpilot
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“Was my first time buying a product from Ubuy, but I found it so helpful. This is reliable. Gonna place a new order!”

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